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What factors influence the health status of patients with rheumatoid arthritis measured by the SF-12v2Health Survey and the Health Assessment Questionnaire?
Journal of Rheumatology, 09/14/09

Linde L et al. – The HAQ was more sensitive to differences in demographic, lifestyle, and disease- and treatment-related factors than the SF-12. The established clinical value and feasibility of the HAQ highlights its advantages over the SF-12 in describing health status in RA.

• Clinical and patient-reported data, including the HAQ and SF-12, were collected from RA patient records
• 3 multiple linear regression models were estimated
• HAQ, SF-12 physical component score, and SF-12 mental component score as outcome and sociodemographic, lifestyle, and RA-related treatment and comorbidity characteristics as explanatory variables

• 3156 of 3704 invited patients participated
• 75% women, 76% rheumatoid factor-positive
• Median age 61 years
• Disease duration 7 years
• Disease Activity Score on 28 joints (DAS28) 2.97
• HAQ score 0.63 (range 0–3)
• SF-12 PCS 56 (range 6–99)
• Moderate to high DAS28 and = 3 comorbid conditions had consistently worse HAQ and SF-12 scores compared to reference groups
• Weekly exercise was associated with better scores compared to no exercise

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