Rheumatology Medical News about primary gout;nephrolithiasis

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The prevalence of nephrolithiasis in patients with primary gout: a cross-sectional study using helical computed tomography
Journal of Rheumatology, 09/09/09

Shimizu T et al. – The prevalence of nephrolithiasis obtained using CT was 26.9% in the 383 patients with primary gout. Our results imply that we cannot determine an accurate prevalence of urolithiasis from a patient’s history. Most of the “prevalence” reported in the past may not correspond to a statistically justifiable one, but instead to the “cumulative incidence” during the contraction period of gout. Thus, the prevalence of nephrolithiasis confirmed by a cross-sectional method and the “prevalence” of urolithiasis calculated from patients’ calculus histories should be clearly distinguished.E

Methods

The kidneys of 383 male patients with primary gout were examined using an unenhanced 2-row helical CT detector, imaging at 2 mm collimation and a helical pitch of 3
The urolithiasis history of the 383 patients was investigated by inquiry

Results

CT scans confirmed nephrolithiasis in 103 (26.9%, 95% confidence interval 22.5%–31.6%) of the 383 gouty patients, and history of urinary calculus was positive in 65 (17.0%, 95% confidence interval 13.4%–21.1%) of the 383
However, 64 (62%) of the 103 stone-formers identified by CT had no history of urolithiasis
There was a significant difference between the ages of the 103 stone-formers identified by CT and the 65 stone-formers identified from the history

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