Rheumatology Medical News about systemic sclerosis;serum CXCL16 concentrations;skin sclerosis

Become a Member Today!
Register

Most Viewed Abstracts

1. Report Shows Shift in Starting Salaries for Physicians

2. Rapid correction of low vitamin D status in nursing home residents

3. 2008 Exclusive Survey—Earnings: Good news for primary care income

4. Medicare pay-for-reporting effort draws fire from frustrated doctors

5. Allopurinol-induced recurrent dress syndrome: Pathophysiology and treatment

Your Article Summary

See Latest Articles

(Click the title below to leave the MDLinx Network and go to the Journal's Website)

Serum cxcl16 concentrations correlate with the extent of skin sclerosis in patients with systemic sclerosis
Journal of Rheumatology, 09/10/09

Yanaba K et al. – CXCL16 levels were increased in patients with SSc, and correlated with the extent of skin sclerosis, suggesting that CXCL16 may have a role in the development of skin fibrosis in SSc.

Methods

Serum CXCL16 levels from 89 patients with SSc were examined by ELISA
In a retrospective longitudinal study, 68 sera from 28 patients with SSc were analyzed (followup 1.3 to 7.3 yrs)

Results

Serum CXCL16 levels were elevated in patients with SSc compared with healthy controls (n = 42)
Patients with diffuse cutaneous SSc (n = 52) had higher levels of CXCL16 than those with limited cutaneous SSc (n = 37). Serum CXCL16 levels correlated positively with the extent of skin sclerosis. In the longitudinal study, CXCL16 levels generally decreased on a parallel with the improvement in skin sclerosis

<< Previous
Association of severe inflammatory polyarthritis in primary...

Next >>
Emotion regulation in patients with rheumatic diseases: validity...