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See Latest ArticlesElderly Onset Rheumatoid Arthritis: Differential Diagnosis and Choice of First-Line and Subsequent Therapy
Drugs & Aging, 09/08/09
Villa–Blanco JI et al. – The differential diagnosis of EORA from other rheumatological disorders that are prevalent in this stratum of the population, such as polymyalgia rheumatica, crystal–induced arthritis or osteoarthritis, may be complicated because these disorders can present with signs and symptoms similar to those of RA in some circumstances. A prompt diagnosis of true RA is important because early treatment should be implemented. It is recommended that therapy of EORA be tailored according to disease activity, with the aim of achieving clinical remission or the lowest possible level of disease activity in order to minimize potential functional sequelae. Co–morbidities and drug toxicity profiles are major considerations when choosing the most suitable therapy for EORA patients. Prudent use and careful follow–up of all treatments are also required because of the increased risk of adverse events in elderly patients. However, no special contraindications to the use of disease–modifying antirheumatic drugs in this age group apply, and use of biological therapies currently used in younger RA patients has also been described in these patients.
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