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See Latest ArticlesHot topic: Utilization of Biology Therapy in Spondyloarthropathy (SpA) in Asia Countries
Current Rheumatology Reviews, 09/14/09
Chou C–T – Before the era of biologic agents, NSAIDs were only drugs proved to be useful in treating patients with SPA. However, approximately 20% are non–responder. From the serologic, synovial fluid and synovial pathology findings, TNF–alpha is highly associated with AS or other SPA. Early studies of anti–TNF–alpha therapy in SPA showed a very good efficacy for pain and inflammation as in RA. However, it is not certain for the biologic therapy to reduce the new bone formation in AS. This is still a treatment barrier but need to break through.
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An epidemiological survey of low back pain and axial spondyloarthritis in a Chinese Han population
Scandinavian Journal of Rheumatology , 11/24/09
The chromosome 16q region associated with ankylosing spondylitis includes the candidate gene TRADD (TNF receptor type 1-associated death domain)
Annals of Rheumatic Diseases, 11/13/09
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