Rheumatology Medical News about older, nonosteoporotic men; calcium supplementation

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Can healthy, older, nonosteoporotic men benefit from calcium supplementation?
Current Osteoporosis Reports, 09/10/09

Lee C – This trial offers supportive evidence on the benefi cial effect of 1200 mg/day of calcium citrate on BMD when given in divided doses in older, non–osteoporotic men. Although increases in BMD were shown at both the hip and lumbar spine, the increase was more rapid at the lumbar spine. In contrast, 600 mg/day of calcium citrate failed to demonstrate any notable improvements in BMD as compared with placebo. Yet, the levels of calcium intake appeared to correspond with dose–related reductions in PTH, P1NP, and ALP activity in a subgroup of subjects whose serum levels were measured. The absence of an improvement in BMD with supplementation of 600 mg/day of calcium citrate, despite reductions in PTH, P1NP, and ALP activity, is not entirely inconsistent with previous findings.

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