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Spa therapy in the treatment of knee osteoarthritis, a large randomised multicentre trial.
Annals of Rheumatic Diseases, 09/08/09

Forestier R et al. – For patients with knee OA a 3 week course of spa therapy together with home exercises and usual pharmacological treatments offers benefit after 6 months compared to exercises and usual treatment alone, and is well tolerated.

• Large multicentre randomised prospective clinical trial of patients with knee osteoarthritis
• Zelen randomisation was used so patients were ignorant of the other group and spa personnel were not told which patients were participating

• The intention to treat analysis included 187 controls and 195 spa therapy patients
• At 6 months, 99/195 (50.8%) spa group patients had Minimal Clinically Important Improvement and 68/187 (36.4%) of controls
• However, no improvement in quality of life (SF36) or Patient Acceptable Symptom State was observed at 6 months

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