Rheumatology Medical News about chondrocytes

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Chondrogenic differentiation potential of osteoarthritic chondrocytes and their possible use in matrix-associated autologous chondrocyte transplantation
Arthritis Research & Therapy, 09/02/09

Dehne T et al. – Only few genes were differentially expressed between OA and ND chondrocytes in Hyaff–11 culture. The risk of differentiation into hypertrophic cartilage does not seem to be increased for OA chondrocytes. The findings suggest that the chondrogenic capacity is not significantly affected by OA, and OA chondrocytes fulfill the requirements for matrix–associated ACT.

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Phenotype-related differential alpha-2,6- or alpha-2,3-sialylation of glycoprotein N-glycans in human chondrocytes
Osteoarthritis and Cartilage, 10/23/09 Relevance Score: 88%%

Matrix-assisted autologous chondrocyte implantation into a 14cm2 cartilage defect, caused by steroid-induced osteonecrosis
The Knee, 10/27/09 Relevance Score: 87%%

Increased p21 expression in chondrocytes of achondroplasic children independently from the presence of the G380R FGFR3 mutation
Journal of Orthopaedic Science, 10/06/09 Relevance Score: 87%%

Mitochondrial DNA damage is involved in apoptosis caused by pro-inflammatory cytokines in human OA chondrocytes
Osteoarthritis and Cartilage, 10/23/09 Relevance Score: 84%%

Regulation of prostaglandin E2 synthesis in cells derived from chondrocytes of patients with osteoarthritis
Journal of Orthopaedic Science, 10/06/09 Relevance Score: 84%%