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Disease activity and damage are not associated with increased levels of fatigue in systemic lupus erythematosus patients from a multiethnic cohort: LXVII
Arthritis Care and Research , 09/01/09
Burgos PI et al. – The presence of pain, abnormal illness-related behaviors, helplessness, and constitutional manifestations were associated with increased levels of fatigue. However, SLE-specific measures, such as disease activity and damage, were not.
Methods- Patients with SLE (according to the American College of Rheumatology revised and updated criteria) age 16 years with a disease duration 5 years at entry into the cohort, and of Hispanic (Texan or Puerto Rican), African American, or Caucasian ethnicity were studied
- A total of 515 patients (91% female) contributed 2,609 visits to these analyses
- Variables associated with increased levels of fatigue in the multivariable analyses were Caucasian ethnicity, the presence of constitutional symptoms (fever, weight loss), and higher levels of pain, abnormal illness-related behaviors, and helplessness
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