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Neurologic signs and symptoms in fibromyalgia
Arthritis & Rheumatism, 09/01/09

Watson NF et al. – The FM group had more neurologic symptoms than did the controls, with moderate correlation between symptoms and signs.

• Persons with FM (n = 166) and pain-free controls (n = 66) underwent systematic neurologic examination by a neurologist blinded to disease status
• Neurologic symptoms lasting at least 3 months were assessed with a standard questionnaire
• Within the FM group we examined the correlation between self-reported symptoms and physical examination findings

• Age- and sex-adjusted estimates revealed that compared with the control group, the FM group had significantly more neurologic abnormalities in multiple categories, including greater dysfunction in cranial nerves IX and X (42% versus 8%) and more sensory (65% versus 25%), motor (33% versus 3%), and gait (28% versus 7%) abnormalities
• Similarly, the FM group had significantly more neurologic symptoms than the control group in 27 of 29 categories, with the greatest differences observed for photophobia (70% versus 6%), poor balance (63% versus 4%), and weakness (58% versus 2%) and tingling (54% versus 4%) in the arms or legs. Poor balance or coordination, tingling or weakness in the arms or legs, and numbness in any part of the body correlated with appropriate neurologic examination findings in the FM group

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