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Fibronectin fragments mediate matrix metalloproteinase upregulation and cartilage damage through proline rich tyrosine kinase 2, c-src, NF-kB and protein kinase C-delta
Osteoarthritis and Cartilage , 08/28/09
Ding L et al. – These studies enhance our knowledge of crucial factors in Fn–f mediated signaling in MMP upregulation and cartilage damage and because of the potential physiologic relevance of Fn–fs, provide a better knowledge of cartilage degeneration in general.
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