Rheumatology Medical News about hand osteoarthritis;serum hyaluronic acid;

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Serum hyaluronic acid as a potential marker with a predictive value for further radiographic progression of hand osteoarthritis
Osteoarthritis and Cartilage , 08/27/09

Filkova M et al. – HA is increased in patients with erosive HOA and could be proposed as a surrogate marker with a predictive value for further radiographic progression of HOA.

Methods

55 women with erosive and 33 women with non-erosive HOA
Serum levels of HA were measured by ELISA

Results

Serum levels of HA were significantly higher in patients with erosive than with non-erosive HOA
Serum levels of HA correlated significantly with the number of hand joints with deviations and deformities
HA adjusted for age and disease duration signifiantly correlated with radiographs at baseline and after 2 y in all patients with HOA

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