Rheumatology Medical News about osteoarthritis;glucosamine;ibuprofen;cartilage turnover;physical training

Become a Member Today!
Register

Most Viewed Abstracts

1. Report Shows Shift in Starting Salaries for Physicians

2. Rapid correction of low vitamin D status in nursing home residents

3. 2008 Exclusive Survey—Earnings: Good news for primary care income

4. Medicare pay-for-reporting effort draws fire from frustrated doctors

5. Allopurinol-induced recurrent dress syndrome: Pathophysiology and treatment

Your Article Summary

See Latest Articles

(Click the title below to leave the MDLinx Network and go to the Journal's Website)

Glucosamine but not ibuprofen alters cartilage turnover in osteoarthritis patients in response to physical training
Osteoarthritis and Cartilage , 08/27/09

Petersen SG et al. – Serum COMP decreased significantly over the 12-week training period when treatment with glucosamine was added to the training regimen.

Methods

12 week double-blind, placebo-controlled, randomized study
36 elderly patients with bilateral tibiofemoral knee OA randomly assigned to tx with glucosamine, ibuprofen, or placebo during 12 weeks of strength training of both legs
Serum COMP and urinary CTX-II were measured by ELISA

Results

All 3 groups increased their muscle strength following 12 weeks of strength training
Serum COMP levels were reduced in the glucosamine-treated group after the training period, but did not change in the other 2 groups
Glucosamine reduced COMP compared to both placebo and ibuprofen
The mean reduction with glucosamine was 13% vs. placebo and 17% vs. ibuprofen

<< Previous
Serum hyaluronic acid as a potential marker with a predictive...

Next >>
Hypovitaminosis D is associated with greater body mass index and...

There Is Inadequate Evidence to Determine the Effectiveness of Nonpharmacological and Nonsurgical Interventions for Hand Osteoarthritis: An Overview of High-Quality Systematic Reviews
Physical Therapy, 11/10/09 Relevance Score: 90%

The Safety of Flavocoxid, a Medical Food, in the Dietary Management of Knee Osteoarthritis
Journal of Medicinal Food, 10/30/09 Relevance Score: 89%

Discriminant Validity of the Western Ontario and McMaster Universities Osteoarthritis Index Physical Functioning Subscale in Community Samples With Hip Osteoarthritis
Archives of Physical Medicine and Rehabilitation, 10/22/09 Relevance Score: 89%

Clinical efficacy evaluation on electroacupuncture for osteoarthritis and observation on biomechanical indexes
Journal of Acupuncture and Tuina Science, 10/19/09 Relevance Score: 89%

Effect of nonsteroidal anti-inflammatory drug plasters for knee osteoarthritis in Japanese: a randomized controlled trial
Modern Rheumatology, 10/12/09 Relevance Score: 89%