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See Latest ArticlesAmyloidosis is frequently undetected in patients with rheumatoid arthritis
Amyloid The Journal of Protein Folding Disorders, 08/28/09
Koivuniemi R et al. – In patients with active and long-lasting RA, a systematic search for amyloid may enable early dx of amyloidosis, which will require effective suppression of inflammation
Methods- Retrospective study
- Amyloid was re-examined in tissue samples and the detection rate was compared with the original autopsy reports of 369 consecutively autopsied RA patients and 370 non-RA patients
- Re-examination of 90% of the 739 cases showed a doubling of the prevalence of amyloid compared with the original reports (18% to 30 in RA and 2% to 4% in non-RA)
- In RA patients, cardiac amyloid was as frequent as renal amyloid
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Today in Rheumatoid Arthritis...keeping you current
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CTLA4-Ig interacts with cultured synovial macrophages from rheumatoid arthritis patients and downregulates cytokine production
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