Rheumatology Medical News about hyperuricemia

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A study of rasburicase for the management of hyperuricemia in pediatric patients with newly diagnosed hematologic malignancies at high risk for tumor lysis syndrome
International Journal of Hematology, 08/27/09

Kikuchi A et al. – Two hypersensitivity reactions, including grade 1/2 pruritus, were considered to be related to rasburicase. Rasburicase is effective and well tolerated for the management of hyperuricemia in Japanese pediatric patients at high risk of developing TLS.

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Hyperuricemia Is a Mediator of Endothelial Dysfunction and Inflammation in Renal Allograft Recipients
Transplantation Proceedings, 11/02/09 Relevance Score: 89%%

Hyperuricemia Is a Mediator of Endothelial Dysfunction and Inflammation in Renal Allograft Recipients
Transplantation Proceedings, 10/30/09 Relevance Score: 87%%

Efficacy and Safety of Losartan in Treatment of Hyperuricemia and Posttransplantation Erythrocytosis: Results of a Prospective, Open, Randomized, Case-Control Study
Transplantation Proceedings, 11/23/09 Relevance Score: 85%%

Homozygous SLC2A9 Mutations Cause Severe Renal Hypouricemia
Journal of the American Society of Nephrology, 11/20/09 Relevance Score: 80%%

Acute, food-induced moderate elevation of plasma uric acid protects against hyperoxia-induced oxidative stress and increase in arterial stiffness in healthy humans
Atherosclerosis, 11/17/09 Relevance Score: 80%%