Your Messages Inbox
Most Viewed Abstracts
1. Report Shows Shift in Starting Salaries for Physicians 2. Rapid correction of low vitamin D status in nursing home residents 3. 2008 Exclusive Survey—Earnings: Good news for primary care income 4. Medicare pay-for-reporting effort draws fire from frustrated doctors 5. Allopurinol-induced recurrent dress syndrome: Pathophysiology and treatment
Top Ten Searches
rheumatoid arthritis lupus polymyalgia sjogrens fibromyalgia amyloidosis vasculitis urate raynauds myositisYour Article Summary
See Latest ArticlesSmoking is associated with increased cartilage loss and persistence of bone marrow lesions over 2 years in community-based individuals
Rheumatology, 08/25/09
Davies-Tuck ML et al.Smoking has a detrimental effect on joint cartilage, which may be mediated by impairing bone marrow lesions (BMLs) to resolve.
Methods- 271 had a MRI of the dominant knee at baseline and 2 y later
- Cartilage volume and BMLs were measured
- Smokers had an increased annual loss of medial, but not lateral or patellar carilage volume
- A relationship existed between increasing pack-years and increased medial cartilage volume loss
- BMLs were 11.4 times more likely to persist in smokers than never smokers
Miranda Davies-Tuck, 08/31/09
| This is the first longitudinal study to examine the relationship between smoking and change in cartilage volume in an asymptomatic, community based population. The persistence of the BML was found to partially mediate the relationship between smoking and cartilage loss. The results suggests that the detrimental effect of cigarette smoking on cartilage maybe be partially mediated via the effect of cigarette smoke reducing the capacity of the BML to resolve. |
Today in Basic Science/Genetics...keeping you current
Receive free subspecialty "5-minute updates" via email
Effect of Glucocorticoid-, Parathyroid- and Thyroid Hormones Excess on Human Iliac Crest Bone Matrix Insulin-like Growth Factor (IGF)-I in Patients with Osteoporosis
Experimental and Clinical Endocrinology & Diabetes, 12/09/09
Mitochondrial DNA haplogroups modulate the serum levels of biomarkers in patients with osteoarthritis
Annals of Rheumatic Diseases, 12/09/09
ITGAM coding variant (rs1143679) influences the risk of renal disease, discoid rash, and immunologic manifestations in lupus patients with European ancestry
Annals of Rheumatic Diseases, 12/09/09
Sponsor
Article Search
Sponsor