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Effects of inflammation on cholesterol metabolism: Impact on systemic lupus erythematosus
Current Rheumatology Reports, 08/21/09
Reiss AB – The relationship between the inflammatory state and dyslipidemia in lupus is complex, involving lipoproteins, cholesterol transporters, scavenger receptors, and oxysterols. The impact of lupus on each of these components of the cholesterol flux pathways is discussed. The formation of autoantibodies against epitopes within lipoprotein particles and their controversial role in atherogenesis is addressed.
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