Rheumatology Medical News about Glucocorticoid, Osteoporosis, Prophylaxis

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Glucocorticoid-induced osteoporosis: Unawareness or negligence in India?
International Journal of Rheumatic Diseases, 08/20/09

Gera C et al. – This study shows poor pre-therapeutic risk assessment, absence of instructions regarding preventive measures, inappropriate investigation for presence of osteoporosis, and unacceptable absence of bone protective agents in patients receiving long-term glucocorticoid therapy.

Methods

Burden of osteoporosis is on the rise and glucocorticoids are one of the leading causes of drug-induced osteoporosis
Pts on long-term glucocorticoid therapy should receive adequate prophylaxis to prevent osteoporosis
This study was undertakent to identify prescribing trends for prophylaxis and management of steroid-induced osteoporosis
A retrospective audit for pts to determine whether clinicians are evaluating and following prophylactic guidelines for corticoid-induced osteoporosis:
- Information regarding risk assessment for osteoporosis
- Instructions regarding its prevention
- Bone mineral density (BMD) measurements, and
- Prophylactic therapy were recorded

Results

105 pts (38 men), >18 yrs of age were included in this study
56% had at least 1 documented intervention for osteoporosis prevention (calcium, vit D, bisphosphonates or a BMD study)
Only 3 pts received bisphosphonates for osteoporosis prophylaxis

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Effects of Alendronate on Bone Metabolism in Glucocorticoid-Induced Osteoporosis Measured by 18F-Fluoride PET: A Prospective Study
The Journal of Nuclear Medicine, 11/02/09 Relevance Score: 67%

Teriparatide Outperforms Alendronate In Treating Steroid-induced Osteoporosis
ScienceDaily, 10/30/09 Relevance Score: 67%

Effects of teriparatide versus alendronate for treating glucocorticoid-induced osteoporosis: Thirty-six-month results of a randomized, double-blind, controlled trial
Arthritis & Rheumatism, 11/03/09 Relevance Score: 66%

Osteologix to Continue Development of Osteoporosis Drug
Internet Source, 10/21/09 Relevance Score: 46%

Lifestyle increases osteoporosis risk: docs
Internet Source, 10/21/09 Relevance Score: 45%