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The IL-1 inhibitor rilonacept in treatment of chronic gouty arthritis: results of a placebo-controlled, monosequence crossover, nonrandomized, single-blind pilot study
Annals of Rheumatic Diseases, 08/05/09
Terkeltaub R et al. – This proof–of–concept study demonstrated that rilonacept is generally well tolerated and may offer therapeutic benefit in reducing pain in patients with chronic refractory gouty arthritis, supporting the need for larger, randomized, controlled studies of IL–1 antagonism such as with rilonacept for this clinical indication.
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