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Intra-articular corticosteroids in the treatment of juvenile idiopathic arthritis: Safety, efficacy, and features affecting outcome. A comprehensive review of the literature
Open Access Rheumatology: Research and Reviews, 08/03/09

Gotte AC et al. – This review examines the rationale, efficacy, safety, and application of the use of intra-articular corticosteroid injection (IACI) in the treatment of juvenile idiopathic arthritis (JIA), focusing on factors that affect the outcome following IACI.

• IACI is a safe and effective treatment option in the management of JIA, particularly oligoarthritis
• Use of IACI can:
  • Control disease activity and induce resolution of synovitis
  • Decrease the presence of joint and limb deformities
  • Improve function
  • Provide pain relief, and
  • Serve as an adjunct to minimize more toxic treatments
• Various technical aspects, patient characteristics, and disease features impact the efficacy ofIACI
• Data on adverse effects support that IACI is a safe treatment option, with the majority of reported AEs being of minimal clinical significance

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