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See Latest ArticlesGolimumab: A novel human anti-TNF-alpha monoclonal antibody for the treatment of rheumatoid arthritis, ankylosing spondylitis, and psoriatic arthritis
Core Evidence, 07/31/09
Kay J et al. – Golimumab has demonstrated significant efficacy in randomized, double–blind, placebo–controlled trials when administered subcutaneously once every four weeks. It has been generally well tolerated in clinical trials and demonstrates a safety profile comparable with currently available TNF–alpha inhibitors. Golimumab has been confirmed to be an effective treatment for patients with RA, PsA, and AS in phase III clinical trials as evaluated by traditional measures of disease activity, such as signs and symptoms, as well as measures of physical function, patient reported outcomes, and health economic measures. The efficacy and safety profile of golimumab in RA, PsA, and AS appears to be similar to other anti–TNF agents. However, golimumab has the potential advantage of once monthly subcutaneous administration and the possibility of both subcutaneous and intravenous administration.
Today in Clinical Pharmacology...keeping you current
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Treatment of polymyalgia rheumatica
Archives of Internal Medicine, 11/10/09
Osteonecrosis of the jaw correlated to bisphosphonate therapy in non-oncologic patients: Clinicopathological features of 24 patients
Journal of Rheumatology, 11/09/09
Osteoarthritis: A review of treatment options
Geriatrics, 10/21/09
Today in Other Arthritis...keeping you current
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Hepatoprotective effect of TNF-alpha blockade in psoriatic arthritis: A cross-sectional study
Annals of Rheumatic Diseases, 11/09/09
The use of complementary and alternative medicine in outpatients with inflammatory rheumatic diseases in Sweden
Scandinavian Journal of Rheumatology , 11/17/09
Update in treatment options for psoriatic arthritis
Expert Review of Clinical Immunology, 11/23/09
Today in Rheumatoid Arthritis...keeping you current
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Treatment of polymyalgia rheumatica
Archives of Internal Medicine, 11/10/09
Cancer risk in patients with rheumatoid arthritis treated with anti-tumor necrosis factor [alpha] therapies: Does the risk change with the time since start of treatment?
Arthritis & Rheumatism, 11/05/09
Does rheumatoid arthritis equal diabetes mellitus as an independent risk factor for cardiovascular disease? A prospective study
Arthritis Care and Research , 11/03/09
Today in Spondylarthropathies...keeping you current
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Erythrocyte sedimentation rate, CRP level, and serum amyloid a protein for patient selection and monitoring of anti-tumor necrosis factor treatment in ankylosing spondylitis
Arthritis Care and Research , 11/02/09
Agreement between quantiferon-TB gold test and tuberculin skin test in the identification of latent tuberculosis infection in patients with rheumatoid arthritis and ankylosing spondylitis
Journal of Rheumatology, 11/18/09
Recreational Exercise in Rheumatic Diseases
International Journal of Sports Medicine, 10/30/09
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