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See Latest ArticlesMeasurement properties of the medical outcomes study sleep scale in patients with fibromyalgia
Sleep Medicine, 07/31/09
Cappelleria JC et al. – Study concludes that the Medical Outcomes Study (MOS) Sleep Scale is an appropriate measure of fibromyalgia (FM)-related sleep problems; provides the foundation for further use and evaluation of the MOS Sleep Scale in FM pts.
Methods- An evaluation of MOS Sleep Scale as a measure of FM-related sleep problems
- Analyses based on data from 1056 and 1077 studies: 2 randomized, double-blind, placebo-controlled trials of pregabalin for adults with FM
- MOS Sleep Scale scores of study pts were compared with US normative scores using a one-sample Z test
- Subscale structure of the MOS was evaluated by confirmatory factor analyses
- Internal consistency was evaluated using Cronbach’s alpha reliability coefficients
- Estimated clinically important differences (CID) in MOS Sleep Disturbance subscale scores were evaluated using mixed-effects models of change in subscale scores as a function of the Patient Global Impression of Change (PGIC)
- 1056 and 1077 studies included 748 and 745 pts, respectively
- Most pts were female and white; mean ages were 48.8 yrs and 50.1 yrs
- Baseline MOS Sleep Scale scores were poorer than general population values
- MOS subscale structure was confirmed in both studies at each assessment except at baseline in the 1056 study
- Cronbach’s alpha coefficients were acceptable, for all multi-item scales at baseline and end-of-study assessments in both studies, except Sleep Adequacy subscale at baseline
- The estimated CID for the MOS Sleep Disturbance subscale was 7.9
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