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Angiogenic growth factors inhibit chondrocyte ageing in osteoarthritis: potential involvement of catabolic stress-induced overexpression of caveolin-1 in cellular ageing
International Journal of Rheumatic Diseases, 07/17/09
Yudoh K et al. – The results suggest that AGFs downregulated IL–1–beta–induced chondrocyte ageing and overexpression of caveolin–1 in human chondrocytes, which is mediated by kinase cascades involving the p42/44 MAP kinase and PI3–K/Akt signalling pathways.
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Today in Basic Science/Genetics...keeping you current
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TNF{alpha} blockade therapy reduces circulating NT-proBNP levels in RA patients with active disease: Results from prospective cohort study
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Serum levels of proinflammatory cytokines interleukin-1[beta], interleukin-6, and tumor necrosis factor [alpha] in mixed cryoglobulinemia
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Today in Osteoarthritis...keeping you current
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Total cholesterol and triglycerides are associated with the development of new bone marrow lesions in asymptomatic middle-aged women - a prospective cohort study
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Radiographic severity of knee osteoarthritis is conditional on interleukin-1 receptor antagonist gene variations
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