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See Latest ArticlesEfficacy of SLZ and MTX (alone or combination) on the treatment of active sacroiliitis in early AS
Rheumatology International, 07/17/09
Kabasakal Y et al. – Study concludes that the ratio of treatment of active sacroiliitis, especially in early period, with sulphasalazine (SLZ) as a disease-modifying antirheumatic drugs (DMARD) is better than methotrexate (MTX) or MTX + SLZ, but this difference is not statistically significant. A prospective study of the treatment of active sacroiliitis by DMARDs may be more illustrative.
Methods- Aim was to study, the effect of SLZ and MTX, which are used alone and in combination, for 6 mo, on treatment of active sacroiliitis
- Treatment shown by dynamic magnetic resonance and acute phase reactants in laboratory
- 55 pts (F:M = 34:21) with active sacroiliitis; mean age = 37.05 + 13.03 year were evaluated and determined by dynamic magnetic resonance imaging
- The better response in the SLZ treatment group than the other 2 groups has been obtained
- Nevertheless, those changes were not statistically different
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