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Uncommon clinical pattern of FMF: Protracted febrile myalgia syndrome
Rheumatology International, 07/15/09
Tufan G et al. – Study describes 30-year-old pregnant Turkish woman with known Familial Mediterranean fever (FMF) and under colchicine prophylaxis, with severe myalgia for 8 weeks, emphasizing the importance of a different clinical pattern of protracted febrile myalgia syndrome (PFMS) even in the absence of other symptoms. Conclusions are:
- The clinical picture of FMF has been expanded appreciably during the past 15 yrs and additional clinical features, including severe myalgia, scrotal swelling, and cardiac involvement, have been described
- Progressive systemic amyloidosis, a situation leading to end stage renal failure is the most important complication of FMF
- Therefore, diagnosing and starting the treatment duly have a great importance
- FMF can be considered to be recognized easily with the classical findings, but much different findings may cause mistakes in diagnosis and treatment
- Like this patient, the only finding may be an atypic course of PFMS with severe myalgia lasted for a long time, which fever and other findings of serositis did not accompany
- Although, similar cases are seen rarely but this rare pattern of a frequently seen disease should be recognized
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