Rheumatology

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Elevated Serum Levels of Arachidonoyl-lysophosphatidic Acid and Sphingosine 1-Phosphate in Systemic Sclerosis
International Journal of Medical Sciences , 07/08/09

Tokumura A et al. - Serum LPA:LPC ratios of two different polyunsaturated phospholipid molecular species, and also the ratio of all species combined, were significantly higher in SSc subjects versus controls. No significant differences were found between other lysophospholipid levels or lysoPLD activities. Elevated 20:4 LPA, S1P levels and polyunsaturated LPA:LPC ratios may be markers for and/or play a significant role in the etiology of SSc and may be future pharmacological targets for SSc treatment.

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Combination of heparin and aspirin is superior to aspirin alone in enhancing live births in patients with recurrent pregnancy loss and positive anti-phospholipid antibodies: A meta-analysis of randomized controlled trials and meta-regression
Rheumatology, 12/08/09

Echocardiography as an Outcome Measure in Scleroderma-related Pulmonary Arterial Hypertension: Results of a Systematic Literature Analysis by the EPOSS Group
Journal of Rheumatology, 12/08/09

Depletion of functionally active CD20+ T cells by rituximab treatment
Arthritis & Rheumatism, 12/07/09

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