Rheumatology Medical News about ankylosing spondylitis;therapeutic approaches

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A systematic medline analysis of therapeutic approaches in ankylosing spondylitis
Rheumatology International, 07/08/09

Goh L et al. – The aim of this review is to equip doctors with the available clinical evidence on the different treatment options in the management of ankylosing spondylitis (AS).

Therapies available that provide persistent control of inflammatory symptoms with improvement in daily function:

NSAIDs remain the first step in patient treatment
Sulphasalazine may be effective in peripheral arthritis; its use in early inflammatory back pain is also reported
Pamidronate and steroid injection into sacroiliac joints (SIJ) have a symptom-modifying effect in AS
Anti-TNF treatment promises early benefit which is likely to continue in the longer term
Treatment with biologics should be considered sooner rather than later in the management of AS

It is emphasized that early diagnosis of AS together with intensive management with biologic agents has the potential for improving patient care as well as reducing the long-term burden of this disease.

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