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Broad-range PCR, cloning and sequencing of the full 16S rRNA gene for detection of bacterial DNA in synovial fluid samples of Tunisian patients with reactive and undifferentiated arthritis
Arthritis Research & Therapy, 07/13/09
Siala M et al. - Broad-range PCR followed by cloning and sequencing the entire 16S rDNA, allowed the identification of the bacterial DNA environment in the SF samples of arthritic patients. The authors found a wide spectrum of bacteria including those known to be involved in ReA and others not previously associated with arthritis.
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