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Effect of baseline quadriceps activation on changes in quadriceps strength after exercise therapy in subjects with knee osteoarthritis
Arthritis Care and Research , 07/06/09
Scopaz KA et al. – Study demonstrates that the baseline quadriceps activation (QA) did not predict changes in quadriceps strength following exercise therapy in patients with knee osteoarthritis (OA). QA measurements using the central activation ratio method may not be helpful in identifying subjects with knee OA who will have difficulty improving quadriceps strength with exercise therapy.
Methods- Aim was to examine whether pretreatment magnitude of QA helps predict changes in quadriceps strength after exercise therapy in pts with knee OA
- 112 subjects with knee OA (70 women); baseline measures included:
- Demographic information
- Quadriceps muscle strength, and
- QA using a burst-superimposition isometric torque test
- Following baseline testing, subjects underwent a 6-wk supervised exercise program
- Program was designed to improve strength, range of motion, balance and agility, and physical function
- On completion, quadriceps strength and QA were reassessed
- Baseline QA was associated with quadriceps strength at baseline, and 2-mo f/u
- Greater magnitude of baseline QA correlated with higher strength
- While controlling for baseline quadriceps strength and type of exercise therapy, the level of QA did not predict quadriceps strength at 2-mo f/u
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