Rheumatology Medical News about juvenile idiopathic arthritis;Wallace Criteria;clinical remission

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Accuracy of Wallace criteria for clinical remission in juvenile idiopathic arthritis: A cohort study of 761 consecutive cases
Journal of Rheumatology, 07/07/09

Lurati A et al. – In this study cohort about one-third of cases obtained a remission episode in 4 decades of observation, with a significant difference between oligoarthritis (OA) and other categories. The remission status duration before a relapse was about 20 months, without a significant difference between juvenile idiopathic arthritis (JIA) categories.

Methods

An evaluation of disease course and clinical usefulness in some categories of JIA
Charts of pts with chronic form of primary (idiopathic) arthritis followed since 1970 were reviewed
Clinical/laboratory variables were collected for further analysis

Results

761 pts; 67.8% female; mean disease onset age: 6.25 yrs; disease mean duration to last visit: 10.02 yrs
Followup mean period was 7.6 ± 6.4 yrs
32.46% pts achieved remission according to criteria:
- Persistent oligoarthritis 153 (42.9%)
- Extended oligoarthritis 15 (13.1%)
- Seronegative polyarthritis 21 (22.4%)
- Systemic arthritis 33 (33.7%)
- Enthesitis related arthritis (ERA) plus juvenile psoriatic arthritis (JPsA) 25 (33.4%)
No pts with seropositive polyarthritis achieved remission status
In remitted pts the mean survival function before relapse was of 20.9 mo overall:
- 21.7 (± 0.46) in persistent oligoarthritis
- 25.0 (± 6.6) in extended oligoarthritis
- 26.7 (± 13.2) in seronegative polyarthritis, and
- 17.6 (± 2.44) in ERA+JPsA