Rheumatology Medical News about rheumatoid arthritis;conventional lipid profile;liipoprotein concentrations

Become a Member Today!
Register

Most Viewed Abstracts

1. Report Shows Shift in Starting Salaries for Physicians

2. Rapid correction of low vitamin D status in nursing home residents

3. 2008 Exclusive Survey—Earnings: Good news for primary care income

4. Medicare pay-for-reporting effort draws fire from frustrated doctors

5. Allopurinol-induced recurrent dress syndrome: Pathophysiology and treatment

Your Article Summary

See Latest Articles

(Click the title below to leave the MDLinx Network and go to the Journal's Website)

Conventional lipid profile and lipoprotein(a) concentrations in treated patients with rheumatoid arthritis
Journal of Rheumatology, 07/02/09

García-gómez C et al. - Rheumatoid arthritis (RA) patients undergoing antirheumatic therapy display a nonatherogenic conventional lipid profile (high HDL-c, low apolipoprotein B concns, and low apolipoprotein B/apolipoprotein A-I ratio). This may be counteracted by the high prevalence of hyperlipoproteinemia(a) observed in these pts.

Methods

An evaluation of conventional lipid risk factors and lipoprotein(a) in treated RA pts
122 pts; lipid profiles of pts were compared with a control group, matched for sex, age, menopausal status, and BMI
Excess lipoprotein(a) was defined by a serum concn >0.3 g/l

Results

High-density lipoprotein cholesterol (HDL-c) concns were higher in pre- and postmenopausal women with RA vs controls
All RA pts had lower levels of apolipoprotein B and apolipoprotein B/apolipoprotein A-I ratio
Postmenopausal women with RA also had lower low-density lipoprotein cholesterol and total cholesterol levels vs controls
No differences observed in serum levels of apolipoprotein A-I and triglyceride
All RA pts had higher lipoprotein(a) values than controls
56% men and 53% and 54% pre- and postmenopausal women with RA, respectively, had hyperlipoproteinemia(a)

Next >>
Cardiovascular involvement in primary systemic vasculitis