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Rheumatoid arthritis is linked to oral bacteria: Etiological association
Modern Rheumatology, 07/01/09

Ogrendik M – Review to evaluate the association between rheumatoid arthritis (RA) and periodontopathic bacteria. The presented evidence indicates that oral bacteria directly associate with etiopathogenesis of RA. Periodontal infections should be treated and prevented from becoming chronic.

• Clinical studies have provided evidence for a significant association between the 2 disorders
• High levels of oral anaerobic bacterial antibodies have been found in the serum and synovial fluid of RA pts
• Porphyromonas gingivalis, Tannerella forsythensis, and Prevotella intermedia have been identified in RA synovial fluid
• Ornidazole, levofloxacin, and clarithromycin are used in the treatment of infections caused by anaerobic bacteria
• These antibiotics have been shown to be effective against RA

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