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Health-related quality of life, employment and disability in patients with Sjögren's syndrome
Rheumatology, 06/29/09

Meijer JM et al. – Findings suggest that Sjögren's syndrome (SS) has a large impact on health-related quality of life (HR-QOL), employment and disability.

• A comparison of HR-QOL, employment and disability of primary and secondary SS (pSS and sSS) pts with the general Dutch population
• HR-QOL, employment and disability were evaluated with SF-36 questionnaire and an employment and disability questionnaire in 235 pts
• Results were compared with Dutch population data matched for sex and age
• Demographical and clinical data associated with HR-QOL, employment and disability were assessed

• Response rate was 83%; SS pts scored lower on HR-QOL than the general Dutch population
• sSS pts scored lower on physical functioning, bodily pain and general health than pSS pts
• Predictors for reduced HR-QOL were:
  • fatigue, tendomyalgia, articular involvement,
  • use of artificial saliva, use of anti-depressants, comorbidity,
  • male sex and eligibility for disability compensation (DC)
• Employment was lower and DC rates were higher in SS pts vs Dutch population

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