Your Article Summary
See Latest ArticlesBone mineral density in the hand as a predictor for mortality in patients with rheumatoid arthritis
Rheumatology, 06/29/09
Book C et al. – Findings demonstrate that low digital X-ray radiogrammetry-bone mineral density (DXR-BMD) predicted overall mortality in age- and sex-adjusted analyses; further supporting it as a valid measurement of disease activity or damage and as having prognostic value.
Methods- Aim was to evaluate DXR-BMD in the hand as a predictor for all-cause mortality in RA pts
- 152 consecutive pts (78% women, mean disease duration: 14.2 yrs)
- X-rays of the hands at inclusion were available in 108 pts
- Reasons for not evaluating DXR in 24 pts were placement of joint prostheses or severe malalignment
- BMD was evaluated by DXR on the same digitized hand X-rays used for scoring radiographic joint damage
- 62 of the 82 pts died, corresponding to a standardized mortality ratio of 2.92 for both sexes combined
- In age- and sex-adjusted proportional hazards models, BMD, Steinbrocker functional class 3-4, the physician's global assessment, and ESR were significant predictors of mortality
- However RF, disease duration, Larsen index, Ritchie articular index and the patient's global assessment were not
Related Articles
Efficacy of roxithromycin in adult patients with rheumatoid arthritis who had not received disease-modifying antirheumatic drugs: A 3-month, randomized, double-blind, placebo-controlled trial
Clinical Therapeutics, 10/15/09
Relevance Score: 71%
Certolizumab Pegol: In Rheumatoid Arthritis
BioDrugs, 11/11/09
Relevance Score: 70%
Assistive technology for rheumatoid arthritis
Cochrane Reviews, 10/09/09
Relevance Score: 70%
Treatment of early RA with infliximab is beneficial
American Pharmacists Association, 11/06/09
Relevance Score: 69%
Abatacept for rheumatoid arthritis
Cochrane Reviews, 10/09/09
Relevance Score: 69%
Today in Bone Metabolism...keeping you current
Receive free subspecialty "5-minute updates" via email
Use of bisphosphonates in the treatment of pediatric osteoporosis
International Journal of Clinical Rheumatology, 12/04/09
Vitamin K2 supplementation does not influence bone loss in early menopausal women: A randomised double-blind placebo-controlled trial
Osteoporosis International, 12/03/09
A perspective on male osteoporosis
Best Practice & Research: Clinical Rheumatology, 12/03/09
Today in Rheumatoid Arthritis...keeping you current
Receive free subspecialty "5-minute updates" via email
Comparison of autoinflammation and autoimmunity using TRAPS and rheumatoid arthritis as prototypes of these conditions
International Journal of Clinical Rheumatology, 12/04/09
CTLA4-Ig interacts with cultured synovial macrophages from rheumatoid arthritis patients and downregulates cytokine production
Arthritis Research & Therapy, 11/25/09
No evidence for association of the KLF12 gene with RA in a large UK cohort of >7,000 samples.
Annals of Rheumatic Diseases, 11/23/09