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Emergence of Crohn's Disease During Treatment with the Anti-Tumor Necrosis Factor Agent Etanercept for Ankylosing Spondylitis: Possible Mechanisms of Action
Seminars in Arthritis and Rheumatism, 07/07/09
Haraoui B et al. - The reactivation or the unmasking of gastrointestinal symptoms during etanercept treatment raises the issue of differences between etanercept and the other antitumor necrosis factor monoclonal antibodies in their molecular structure, tumor necrosis factor neutralizing effect, mode of administration, and pharmacokinetics that may account for these observations.
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Today in Clinical Pharmacology...keeping you current
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MLN3897 plus methotrexate in patients with rheumatoid arthritis: Safety, efficacy, pharmacokinetics, and pharmacodynamics of an oral CCR1 antagonist in a phase IIa, double-blind, placebo-controlled, randomized, proof-of-concept study
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An epidemiological survey of low back pain and axial spondyloarthritis in a Chinese Han population
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The chromosome 16q region associated with ankylosing spondylitis includes the candidate gene TRADD (TNF receptor type 1-associated death domain)
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