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Cytochrome C oxidase levels in chondrocytes during monolayer expansion and after return to three dimensional culture
Osteoarthritis and Cartilage , 06/30/09
Boubriak OA et al. - Culture of chondrocytes in monolayer leads to a rapid increase in mitochondrial protein content and cytochrome c oxidase activity. The increase in cytochrome c oxidase activity is not reversed even after chondrocytes are returned to 3-D culture for 4 weeks; high oxygen tension alone does not appear to stimulate cytochrome c oxidase activity.
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