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Which autoantibodies announce that lupus nephritis is on the way
International Journal of Clinical Rheumatology, 06/23/09
Cornec D et al. - Consistent with this view is that titer of anti-dsDNA antibody reflects the presence of lupus nephritis. However, this may rise or drop, before or during a renal flare. Other autoantibodies would thus be of use in monitoring the disease. These include anti-alpha-actinin, anti-C1q and antinucleosome antibodies. Yet, their prognostic value for lupus nephritis must be further investigated. The affinity of related autoantibodies for DNA should perhaps be taken into account, but more instrumental should be antinucleosome, anti-alpha-actinin and anti-C1q antibodies. They are associated together, but each may be combined with high-affinity anti-dsDNA, and particularly with antibodies, to glomerular membrane-associated nucleosomes.
Today in Autoimmune/Heritable...keeping you current
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Genetic background of systemic sclerosis: autoimmune genes take centre stage
Rheumatology, 11/23/09
Identification of anti-prothrombin antibodies in the anti-phospholipid syndrome that display the prothrombinase activity
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T Cell Responses to Steroid Cytochrome P450 21-Hydroxylase in Patients with Autoimmune Primary Adrenal Insufficiency
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Today in Systemic Lupus (SLE)...keeping you current
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Peripheral vascular damage in systemic lupus erythematosus: Data from LUMINA, a large multi-ethnic U.S. cohort (LXIX)
Lupus, 11/28/09
Work disability in systemic lupus erythematosus is prevalent and associated with socio-demographic and disease related factors
Lupus, 11/27/09
The relationship between race, cigarette smoking and carotid intimal medial thickness in systemic lupus erythematosus
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