Rheumatology Journals

Rheumatology

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Mease PJ – TNF plays an important role in several disease states, including rheumatoid arthritis. However, patient responses to these agents in clinical practice may be variable and additional agents are needed. Certolizumab pegol is the only PEGylated anti-TNF that is now approved for the treatment of patients with rheumatoid arthritis. This article summarizes the published efficacy, safety and patient-reported health outcome results for certolizumab pegol in the treatment of patients with active rheumatoid arthritis who have experienced an inadequate response to treatment with DMARDs, including methotrexate.

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