Rheumatology Medical News about gout;hyperuricemia;analysis of urolithiasis;ultrasonography

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Analysis of urolithiasis in patients with gout and hyperuricemia using ultrasonography
Modern Rheumatology, 06/17/09

Okabe H et al. – Study demonstrates that the incidence of urolithiasis in gouty and hyperuricemic patients is feasible by ultrasonography (US) of the abdomen. Correction of the serum uric acid levels, early diagnoses of urolithiasis by US of the abdomen, proper alkalization of urine and sufficient diuresis are the recommended approaches for the management of these pts.

Methods

Aim was to examine the pts with primary gout and asymptomatic hyperuricemia by US in 208 pts; 171 primary gout and 37 asymptomatic hyperuricemia
Incidence of urolithiasis in US of the abdomen, past history and urine occult blood reaction in gouty and hyperuricemic pts was examined
Duration of the current illness was also examined

Results

Total number of ‘positive findings’ in US of the abdomen was 64 out of 208 cases (30.8%)
For these 64 with ‘positive findings’:
- 51.6% had ‘calcification’ or ‘stone formation’ in bilateral kidneys and
- 48.4% showed ‘positive findings’ before the onset of gouty arthritis
Among the 208 cases, 16.3% had a history of urolithiasis
Of the 59 cases with ‘stone formation’ in US of the abdomen, 10.2% showed a positive urine occult blood reaction
Frequency of detecting a ‘positive findings’ was evidently proportional to the detection of this illness

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