Rheumatology

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Health-related quality of life, physical function, fatigue, and disease activity in children with established polyarticular juvenile idiopathic arthritis
Journal of Rheumatology, 06/12/09

Ringold S et al. – Although children in this cohort with polyarticular juvenile idiopathic arthritis (JIA) and inactive disease reported health-related quality of life (HRQOL) scores similar to those of healthy controls, children with polyarticular JIA and their parents/proxies tended to report more fatigue than controls, regardless of disease activity.

• A comparison of child self-report and parent/proxy report of HRQOL, disability, and fatigue in children with active polyarticular JIA vs children with inactive polyarticular JIA and healthy controls
• The Childhood Health Assessment Questionnaire, PedsQL, Generic Core Scales, PedsQL Rheumatology Module, and PedsQL Multidimensional Fatigue Scale were administered
• Disease activity data were collected from the physician clinic notes
• Comparisons were performed with t tests

• 60 children and/or their parents/proxies participated (79% response rate)
• Disease activity status was available for 52; 32 (62%) met criteria for inactive disease
• Participants reported lower scores on the PedsQL Generic Core Scales and the PedsQL Rheumatology Module than those with inactive disease
• Participants also reported lower scores on PedsQL Multidimensional Fatigue Scale vs healthy controls, regardless of disease activity status

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