Your Article Summary
See Latest ArticlesSpinal radiographic changes in ankylosing spondylitis: Association with clinical characteristics and functional outcome
Journal of Rheumatology, 06/16/09
Boonen A et al. – Data demonstrate that the radiographic spinal changes in patients with ankylosing spondylitis (AS) are seen more often in men and those with hip involvement. Bath AS Functional Index (BASFI) status indicates the influence of radiographic changes and hip involvement, but does not reflect the presence of peripheral arthritis and does not differ between men and women.
Methods- Study was undertaken to determine:
- Which pts with AS have radiographic spinal damage and
- Relation between radiographic spinal changes and limitations in physical function
- Treating physician completed a questionnaire including clinical disease manifestations and laboratory findings (HLA-B27 and CRP)
- Spinal radiographs were classified into 3 categories:
- No AS-related spinal abnormalities
- Syndesmophytes; and
- Spinal ankylosis
- Pts completed the BASDAI and the BASFI
- 619 pts fulfilled modified New York criteria for definite AS and had evaluable radiographic data
- 68% were male and disease duration was 17.5 yrs
- Male sex, younger age at symptom onset, and hip involvement were associated with radiographic changes
- However, HLA-B27, peripheral arthritis, and extraarticular disease status (uveitis, psoriasis, and inflammatory bowel disease) were not
- Older age, BASDAI, hip involvement, and spinal change contributed to BASFI
- However, sex, disease duration, peripheral arthritis, and extraarticular manifestations did not
Related Articles
Evaluation of inflammation and oxidative stress in ankylosing spondylitis: a role for macrophage migration inhibitory factor
Modern Rheumatology, 10/05/09
Relevance Score: 69%
Erythrocyte sedimentation rate, CRP level, and serum amyloid a protein for patient selection and monitoring of anti-tumor necrosis factor treatment in ankylosing spondylitis
Arthritis Care and Research, 11/02/09
Relevance Score: 68%
Uncommon case of ankylosing spondylitis associated with spontaneous occurring hypoparathyroidism
Rheumatology International, 11/11/09
Relevance Score: 67%
Concomitant cervical and thoracic spinal fractures in ankylosing spondylitis: A case report and review of literature
Injury Extra, 11/05/09
Relevance Score: 67%
A 2-year comparative open label randomized study of efficacy and safety of etanercept and infliximab in patients with ankylosing spondylitis
Rheumatology International, 10/27/09
Relevance Score: 67%
Today in Spondylarthropathies...keeping you current
Receive free subspecialty "5-minute updates" via email
An epidemiological survey of low back pain and axial spondyloarthritis in a Chinese Han population
Scandinavian Journal of Rheumatology , 11/24/09
The chromosome 16q region associated with ankylosing spondylitis includes the candidate gene TRADD (TNF receptor type 1-associated death domain)
Annals of Rheumatic Diseases, 11/13/09