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See Latest ArticlesBack pain and sacroiliitis in long-standing adult celiac disease: A cross-sectional and follow-up study
Rheumatology International, 06/10/09
Vereckei E et al. – Data suggest the importance of regular rheumatologic follow-up of patients with celiac disease.
Methods- An investigation of whether musculoskeletal manifestations including back pain and sacroiliac joint involvement may be associated with celiac disease
- Rheumatic manifestations were analyzed in 21 adult celiac pts using a comprehensive clinical, laboratory and radiological analysis
- Diagnosis of celiac disease was based on the histopathology of jejunal biopsy specimens
- Mean duration of celiac disease was 15 (0-31) yrs
- All pts were currently on gluten-free diet and none had gastrointestinal symptoms
- Involvement of the sacroiliac joints was confirmed in 70% of celiac pts
- Imaging revealed different morphological changes in the sacroiliac joint:
- Accumulation of synovial fluid
- Synovitis
- Erosion with concomitant sclerosis
- Sacroiliitis or calcification of the ligament
- These changes probably represent different clinical stages and/or manifestations of the same process
- In a f/u study of 8 pts, after 11 yrs on a gluten-free diet, majority of pts had no clinical symptoms
- Yet, a subclinical progression of the sacroiliac joint involvement could be verified
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