Rheumatology

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Is adiposity an under-recognized risk factor for tendinopathy? A systematic review
Arthritis Care and Research , 06/03/09

Gaida JE et al. – Review of observational studies suggest that elevated adiposity is a risk factor for tendon injury, although this association appears to vary depending on aspects of study design and measurement. Further research would determine if reducing adiposity will reduce the risk of tendon injury or improve the results of treatment.

• Aim was to examine the extent and consistency of associations between adiposity and tendinopathy
• 8 electronic databases were searched:
  • Allied and Complementary Medicine
  • Biological Abstracts, CINAHL, Current Contents,
  • EMBase, Medline, SPORTDiscus, and Web of Science
    and citation tracking was performed on included reports
• Studies were included if:
  • they compared adiposity between subjects with and w/o tendon injury or
  • examined adiposity as a predictor of conservative treatment success

• 4 longitudinal cohorts, 14 cross-sectional studies, 8 case-control studies, and 2 interventional studies (28 in total) met the inclusion criteria providing a total of 19,949 individuals
• 18/42 (43%) subpopulations showed elevated adiposity to be associated with tendon injury
• Sensitivity analyses: a clustering of positive findings among studies that included clinical pts (81% positive) and among case-control studies (77% positive)

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