Your Article Summary
See Latest ArticlesInfliximab for reactive arthritis secondary to Chlamydia trachomatis infection
Rheumatology International, 05/29/09
Schafranski MD et al. – Study describes a case of a Chlamydia trachomatis-related reactive arthritis refractory to methotrexate and sulphasalazine that was successfully treated with the monoclonal antibody anti-TNF-α and infliximab. Several pathogens have been linked to the development of reactive arthritis, however no guidelines regarding its treatment are available. Higher serum TNF-α levels in pts with chronic reactive arthritis are reported when compared with pts with the acute form of the disease, suggesting that this pro-inflammatory cytokine may take part in the progress to the chronic form of the disease. This is the first case of effective treatment in a Chlamydia-related situation. Given the response reported here, larger controlled trials are needed to better evaluate the role of these agents.
Related Articles
Infliximab treatment in patients with rheumatoid arthritis and spondyloarthropathies in one rheumatological center: two years drug survival
Rheumatology International, 10/14/09
Relevance Score: 92%
One year study of efficacy and safety of infliximab in the treatment of patients with ocular and neurological Behçets disease refractory to standard immunosuppressive drugs
Rheumatology International, 10/30/09
Relevance Score: 90%
Successful switching to adalimumab in an infliximab-allergic patient with severe Behcet disease-related uveitis
Rheumatology International, 11/02/09
Relevance Score: 88%
A 2-year comparative open label randomized study of efficacy and safety of etanercept and infliximab in patients with ankylosing spondylitis
Rheumatology International, 10/27/09
Relevance Score: 88%
Treatment of early RA with infliximab is beneficial
American Pharmacists Association, 11/06/09
Relevance Score: 87%
Today in Infectious Arthritis...keeping you current
Receive free subspecialty "5-minute updates" via email
Detection of Chlamydia trachomatis- DNA in synovial fluid: evaluation of the sensitivity of different DNA extraction methods and amplification systems
Arthritis Research & Therapy, 11/25/09
CD23 mediates anti-mycobacterial activity of human macrophages
Infection and Immunity, 10/20/09
Arthroscopic synovectomy, an alternative in the treatment of brucellar arthritis of the knee with prolonged course. A report of two cases
The Internet Journal of Orthopedic Surgery, 10/12/09