Rheumatology Medical News about thrombocytopenia;Kawasaki disease

Become a Member Today!
Register

Most Viewed Abstracts

1. Report Shows Shift in Starting Salaries for Physicians

2. Rapid correction of low vitamin D status in nursing home residents

3. 2008 Exclusive Survey—Earnings: Good news for primary care income

4. Medicare pay-for-reporting effort draws fire from frustrated doctors

5. Allopurinol-induced recurrent dress syndrome: Pathophysiology and treatment

Your Article Summary

See Latest Articles

(Click the title below to leave the MDLinx Network and go to the Journal's Website)

Thrombocytopenia as a presenting feature of Kawasaki disease: A case series from North India
Rheumatology International, 06/02/09

Singh S et al. - Article describes six children with Kawasaki disease (KD) who had thrombocytopenia at disease onset. This is an unusual finding and has clinical implications in the diagnosis of this condition.

Like most other vasculitic disorders, the diagnosis of KD is based on clinical features; no laboratory test pathognomonic of the condition is reported
Serum levels of proinflammatory cytokines including IL-6, TNF-α have been shown to be elevated in pts with KD
High levels of IL-6 results in fever and thrombocytosis in conjunction with thrombopoeitin in response to tissue injury
Thrombocytopenia is an unusual finding in KD and has been infrequently reported in the literature
In this study 3 of 6 cases of KD with thrombocytopenia developed coronary artery dilatation which was subsequently resolved on follow up
Thrombocytopenia may, therefore, well be a risk factor for coronary artery abnormalities (CAA) during the acute phase of KD

<< Previous
Parvovirus B19: Its role in chronic arthritis

Next >>
Reactive arthritis: Clinical aspects and medical management