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See Latest ArticlesAltered T-cell subtypes in spondyloarthritis, rheumatoid arthritis and polymyalgia rheumatica
Rheumatology International, 05/20/09
Dejaco C et al. – These findings demonstrate altered T-cell subsets in patients with immune-mediated disease, particularly at sites of inflammation.
Methods- Aim was to assess the prevalences of naive, memory, memory/effector, regulatory and activated T-cells in peripheral blood (PB) and synovial fluid (SF) in pts with
- Spondyloarthritis (SpA, n=22)
- Rheumatoid arthritis (RA, n=15)
- Polymyalgia rheumatica/giant cell arteritis (PMR/GCA, n=38) and
- Healthy controls (HC, n=17)
- Expression of differentiation and activation markers (CD3, CD4, CD8, CD25, CD28, CD45RA, CD45RO) characterizing T-cell subsets were analyzed by flow cytometry
- Frequency of CD3+CD4+CD28? memory/effector T-cells was increased in PB of pts with SpA, RA, and PMR/GCA vs HC
- It tended to be higher in SF of SpA pts
- CD28+CD45RA+CD4+ and CD28+CD45RA+CD8+ naive T-cells were reduced
- CD28+CD45RO+CD4+, CD28+CD45RO+CD8+ memory, CD8+CD25+ activated T-cells, and CD4+CD25hi TREGs were increased in SF vs PB
Today in Basic Science/Genetics...keeping you current
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Hepatoprotective effect of TNF-alpha blockade in psoriatic arthritis: A cross-sectional study
Annals of Rheumatic Diseases, 11/09/09
Musculoskeletal manifestations in patients with malignant disease
Clinical Rheumatology, 11/13/09
The relationship between synovial lymphocyte aggregates and the clinical response to infliximab in rheumatoid arthritis: A prospective study
Arthritis & Rheumatism, 11/04/09
Today in Other Arthritis...keeping you current
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Hepatoprotective effect of TNF-alpha blockade in psoriatic arthritis: A cross-sectional study
Annals of Rheumatic Diseases, 11/09/09
The use of complementary and alternative medicine in outpatients with inflammatory rheumatic diseases in Sweden
Scandinavian Journal of Rheumatology , 11/17/09
Update in treatment options for psoriatic arthritis
Expert Review of Clinical Immunology, 11/23/09
Today in Rheumatoid Arthritis...keeping you current
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Treatment of polymyalgia rheumatica
Archives of Internal Medicine, 11/10/09
Cancer risk in patients with rheumatoid arthritis treated with anti-tumor necrosis factor [alpha] therapies: Does the risk change with the time since start of treatment?
Arthritis & Rheumatism, 11/05/09
Does rheumatoid arthritis equal diabetes mellitus as an independent risk factor for cardiovascular disease? A prospective study
Arthritis Care and Research , 11/03/09
Today in Spondylarthropathies...keeping you current
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Erythrocyte sedimentation rate, CRP level, and serum amyloid a protein for patient selection and monitoring of anti-tumor necrosis factor treatment in ankylosing spondylitis
Arthritis Care and Research , 11/02/09
Agreement between quantiferon-TB gold test and tuberculin skin test in the identification of latent tuberculosis infection in patients with rheumatoid arthritis and ankylosing spondylitis
Journal of Rheumatology, 11/18/09
Recreational Exercise in Rheumatic Diseases
International Journal of Sports Medicine, 10/30/09
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