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Bayesian methods in cost-effectiveness studies: objectivity, computation and other relevant aspects
Health Economics, 05/12/09

Garcia-Donato G et al. - In a probabilistic sensitivity analysis (PSA) of a cost-effectiveness (CE) study, the unknown parameters are considered as random variables. A crucial question is what probabilistic distribution is suitable for synthesizing the available information (mainly data from clinical trials) about these parameters. The authors find that the discrepancies can be quite marked, specially when the number of patients enrolled in the simulated cohort under study is large.

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