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Acute arthropathy in patients with rash diseases: A comparative study
Clinical Rheumatology, 05/11/09
de Oliveira SA et al. – Study reports that arthropathy is a frequent condition in rash diseases, typically with low severity and no specific pattern of joint involvement.
Methods- An assessment of the association of acute arthropathy and selected clinical features in pts with acute rash diseases
- Serum samples from 1,554 pts were tested for anti-measles, dengue, human parvovirus B19, and rubella virus IgM using enzyme immunoassay
- Sera from children, in whom these infections were excluded, were studied for anti-human herpesvirus type 6 IgG Abs using an indirect IFC test
- Joint complaints occurred in 31.2% of the 862 pts with an etiologic diagnosis
- They were more frequently seen in adults than in children
- Among adults, arthropathy prevailed in women compared to men
- Arthropathy was most frequently reported in rubella and in dengue fever cases vs other rash diseases studied
- Joint complaints were more frequently seen in pts with fever and with ≥5 days of onset of the disease regardless of serological diagnosis
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