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See Latest ArticlesUnusual manifestations of the antiphospholipid syndrome
International Journal of Clinical Rheumatology, 05/12/09
Cervera R et al. - Article reviews some of the unusual manifestation of antiphospholipid syndrome (APS):
- APS: characterized by the occurrence of venous and arterial thromboses, recurrent fetal losses and is frequently accompanied by a moderate thrombocytopenia
- APS antibodies: lupus anticoagulant, anticardiolipin antibodies or anti-β2 glycoprotein-I antibodies
- APS can be associated with other diseases, mainly SLE
- Deep vein thrombosis is the most frequently reported manifestation
- Cerebrovascular accidents - either stroke or transient ischemic attacks are the most common arterial thrombotic manifestations
- Early and late fetal losses, premature births and preeclampsia are the most frequent fetal and obstetric manifestations
- Other clinical features: thrombocytopenia, livedo reticularis, heart valve lesions, hemolytic anemia, epilepsy, myocardial infarction, leg ulcers and amaurosis fugax
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