Rheumatology Journals

Rheumatology

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Venhoff N et al. - Risk factors are multifactorial and include a low body mass index, smoking and possibly viral replication itself and antiretroviral treatment. Treatment with tenofovir in particular may induce osteomalacia in some patients. HIV infection is also complicated by osteonecrosis, which is approximately 100-fold more prevalent than in the general population. Biphosphonates represent the first-line therapy for osteoporosis in HIV-infected patients, but their effects on fractures have not yet been evaluated.


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